Shigella flexneri, the pathogen responsible for bacillary dysentery, has evolved multiple strategies to control the inflammatory response.Here, we show that Shigella subverts the subcellular trafficking of the intercellular adhesion molecule-1 (ICAM-1), a key molecule in immune cell recruitment, in a mechanism dependent on the injected bacterial en
During a routine analysis of whistlers on the wide-band VLF recording of the DEMETER satellite, a specific signal structure of numerous fractional-hop whistlers, termed the "Spiky Whistler" (SpW) was identified.These signals appear to be composed of a conventional whistler combined by the compound mode-patterns of guided wave propagation, suggestin
This study investigation is intended to research the dynamic response of horizontally curved bridges under heavy vehicle loads.Most of the main factors that affect the bridge dynamic response due to moving vehicles are considered.An improved 3D grid model, based on commercial software ANSYS Mechanical APDL, is developed for the analysis of curved b
Based on available theoretical and empirical research, the paper demonstrates that although some decline in the product market price competition in the US has been observed, the non-price Bridge Rectifier Diode competition has become more intensive, therefore enhancing competitive constraints.Increased markups (although the magnitude of the change